According to QYResearch statistics, global sales in the ursolic acidmarket reached $7 million in 2024. Given such high demand. Do you have these questions: Is the specification of the Bulk ursolic acid I purchased correct? Has the merchant replaced it with lower-quality ursolic acid to save costs? Is there any way for me to quickly verify the authenticity of bulk ursolic acid? Today, we will teach you a few methods to distinguish genuine bulk ursolic acid.

What is ursolic acid?

Ursolic acid, a triterpenoid compound, is primarily extracted from the leaves of the natural plant rosemary. It appears as a white powder with a distinctive odor. Ursolic acid exhibits various biological effects, including sedative, anti-inflammatory, antibacterial, antidiabetic, anti-ulcer, and blood sugar-lowering properties. It also demonstrates significant Antioxidant activity, making it widely used as a raw material in pharmaceuticals and cosmetics.

How to distinguish genuine bulk ursolic acid?

• Solubility test

Ursolic acid is insoluble in water, but it’s soluble in 2% methanolic potassium hydroxide, hot acetic acid, and moderately in acetone. Ursolic acid is sparingly soluble in alcohols, ether, chloroform, and carbon disulfide. The distinct solubility profile of ursolic acid provides a reliable means for authenticity assessment through simple solubility testing.

• HPLC purity analysis

In the HPLC chromatogram of genuine ursolic acid, the main peak appears at 11-13 minutes with a peak area ratio ≥90%, showing no significant interference from impurities. The baseline noise before and after the main peak is minimal, without abnormal fluctuations. However, in the HPLC chromatogram of adulterated ursolic acid, small uNResolved peaks appear near the main peak, and the main peak may exhibit tailing or fronting. Both observations indicate the presence of impurities mixed with ursolic acid. Therefore, when purchasing ursolic acid, we can request the supplier to run an on-site HPLC test to confirm the product’s purity and authenticity.

• Relevant certificates

We should request bulk ursolic acid suppliers to provide relevant certificates, such as a Certificate of Analysis (COA), GMP certification, and third-party testing reports. If the supplier fails to provide original certificates, or if the testing reports lack official stamps/signatures, or if COA data vary significantly between batches, we can reasonably conclude that their product is unreliable. In such cases, we must avoid purchasing from them.

Common adulteration methods

• Addition of starch or oleanolic acid (a low-cost isomer)
• False purity claims on labels
• Forged test reports

Conclusion

Through this article, we learned how to distinguish genuine bulk ursolic acid from adulterated versions, as well as the common adulteration methods used by suppliers. When purchasing bulk ursolic acid, we can prioritize suppliers who offer free samples and arrange third-party testing for verification. This helps avoid buying adulterated products.

If you are looking for bulk ursolic acid powder, please feel free to purchase from us at any time. We supply bulk 98% ursolic acid powder in large quantities. If other specifications are required, we can also provide them. In addition, we hold certifications including COA, GMP, ISO 9001, ISO 22000, HACCP, KOSHER, and HALAL. As a professional supplier of plant extract powders, we have our factory. We guarantee to provide high-quality products and reliable services, while also having a high price advantage. Welcome to contact us today for quotes and free samples!